Phase I Unit Experience:

·   First-in-human

·   SAD / MAD

·   PK / PD

·   Monoclonal antibodies / Biologics

·   Proof-of-concept

·   Bioavailability / Bioequivalence

·   Crossover designs

·   Food effect

·   Drug-interaction

·   CYP2D6 metabolizers

·   Vaccine

·   Adaptive design

·   Refrigerated centrifuge

Phase I Unit Capabilities:

·   6 bed capacity

·   On-site clinical laboratory

·   On-site investigational pharmacy

·   Holter-Monitoring

·   Neuro-cognitive testing

·   EEG / Polysomnography

·   -40 degree C and -20 degree C

·   Recreation areas for subjects

·   On-site safe parking available

Extensive Experience Facilitating Procedures and Assessments:

·   Polysomnography (nPSG)

·   Multiple Sleep Latency Test (MSLT)

·   Maintenance of Wakefulness Test (MWT)

·   Driving Simulation

·   Actigraphy

·   CPAP Therapy

·   Postural Stability

·   Neurological Assessments of Residual Sedation

·   Vigilance Testing

·   Reaction Time

·   Memory Testing

·   Spirometry